Sotheby’s will auction off 44 pieces of jewelry from the collections of Estee and Evelyn Lauder.

Thirty-three jewels from Evelyn Lauder will support the Breast Cancer Research Foundation, which she founded.

The remaining pieces from the collection of Estee Lauder will benefit the Alzehimer’s Drug Discovery Foundation.

Among the highlights is a ruby, emerald and diamond Cartier Tutti Frutti bracelet estimated at $750,000 to $1-million.

The auction is set for December 9 in New York City.

Estee Lauder, 95, died in 2004.

She’s the founder of the fragrance and skincare products company that bears her name.

Daughter-in-law Evelyn Lauder, 75, died in 2011.

Sotheby’s previously sold jewels from their collections in 2012 and 2013 to benefit breast cancer research.