It seems having a big financial setback can reduce your life expectancy.

A new study finds middle-aged Americans who experienced a sudden, large economic blow were more likely to die during the following years than those who didn’t.

And the heightened danger of death after a devastating loss, which researchers called a wealth shock, crossed socio-economic lines.

The analysis of nearly nine-thousand people’s experiences underscores well-known connections between money and well-being. Prior studies link lower incomes and rising income inequality with more chronic disease and a shorter life.

Lead researcher Lindsay Pool at Northwestern University in Illinois says stress, delays in health care, substance abuse and suicides may contribute.