Jan 12, 2015
By Bob Sheppard
Smokers’ bodies handle nicotine differently, and that can make a difference in how they can quit the habit.
That’s the finding of a study published in Lancet Respiratory Medicine in which the quit rate of smokers using a nicotine patch was compared to those using the quit-smoking drug Champix.
The study, led by Rachel Tyndale of the Centre for Addiction and Mental Health in Toronto, described two groups of smokers: the 60 percent who are “normalized metabolizers” of nicotine, and the rest who are “slow metabolizers.”
The study found that normal metabolizers usually went through more cigarettes per day, and for them it was harder to quit since the nicotine was elimited from their bodies much quicker. They were found to be more than twice as likely to stay off cigarettes after 11 weeks of being on Champix, compared to those using the patch.
Slow metabolizers benefited more from the patch.